|
KMID : 0351219930250030249
|
|
Korean Journal of Infectious Diseases
1993 Volume.25 No. 3 p.249 ~ p.252
|
|
|
Esophageal Ulceration Induced by Zidovudine in a Patient with AIDS
|
|
|
|
|
Abstract
|
|
|
Zidovudine is an important drug which has been shown to prolong the survival in patients with human immunodeficiency virus (HIV) infection. However some adverse reactions such as bone marrow suppression and gastrointestinal disturbances such as a
nausea
and vomiting have been observed.
Recently, we experienced a case. of esophageal ulceration in a patient with acquired immunodeficiency syndrome (AIDS) on the Zidovudine therapy.
A 33-year-old female who received Zidovudine developed a swallowing difficulty substernal chest pain. At endoscopy multiple esophageal ulcerations were seen in the distal esophagus. Histologic examination revealed necrotic inflammation and no
viral
inclusions or fungi were seen. After discontinuing Zidovudine her symptoms resolved completely. Endoscopic follow-up after 2 weeks showed marked healing of ulcerations.
We report this case with a review of the literature.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|